Additionally, they recommend cautious use of radiotherapy, particularly in young patients. Exact extent of clearance under debate, currently no consensus as to adequate margin width, while 10 mm is generally considered acceptable (NCCN Guidelines: Breast Cancer - Phyllodes Tumor [Accessed 2 July 2020], Ann Surg Oncol 2019;26:2747) Axillary dissection not indicated Phyllodes tumors are most common in women in their 40s, but women of any age can have them. Those with an associated invasive cancer should undergo adjuvant systemic therapy based on the stage and hormone receptor status, as outlined online, in these guidelines, at www.NCCN.org . Without prospective trials to guide management, NCCN also recommends consideration of radiation therapy (XRT). Grabowski J, Salzstein SL, Sadler GR, Blair SL. Soft Tissue Sarcoma. Malignant phyllodes tumors: a review of 752 cases. Version 2.2016. malignant phyllodes tumor of the breast were followed up at 3 monthly intervals. NCCN Clinical practice guidelines in oncology (NCCN Guidelines). According to NCCN guidelines wide excision means excision with the intention of obtaining surgical margins ≥1 cm. DCIS-1 NCCN Guidelines for the Management of Phyllodes Tumor. Current guidelines for phyllodes tumor recommend against axillary dissection and chemotherapy use. INTRODUCTION: National Comprehensive Cancer Network (NCCN) guidelines recommend wide excision without axillary staging to treat phyllodes tumors of the breast. Updates in Version 2.2016 of the NCCN Guidelines for Breast Cancer from Version 1.2016 include: Phyllodes tumors (FILL-odes or full-OH-deez) can also be spelled phylloides tumors (full-OY-deez). The National Comprehensive Cancer Network (NCCN ) makes no representations or The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Breast Cancer include up-to-date recommendations for the clinical management of patients with carcinoma in situ, invasive breast cancer, Paget disease, phyllodes tumor, inflammatory breast cancer, and breast cancer … Patient management was examined using NCCN guidelines to determine the relative adherence of providers to established treatment recommendations . The median follow up was 11 months with a range of 4-33 months. National Comprehensive Cancer Network (NCCN). Available at: www.nccn.org (Accessed on February 22, 2016). Am Surg 2007; 73:967. Locally recurrent breast mass following excision of phyllodes tumor Metastatic disease 1 Pathology should be reviewed to assess for fibroadenoma versus phyllodes (phyllodes benign, borderline and malignant). 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